The MOV10 Polyclonal Antibody (CAB7227) is specifically designed for research involving MOV10, an RNA helicase that plays key roles in RNA processing and gene regulation. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the MOV10 protein, researchers can detect and analyze its expression in various cell types, making it an ideal tool for studies in RNA biology and gene regulation.MOV10 is a crucial player in RNA metabolism, acting as an RNA helicase that unwinds RNA structures and regulates RNA stability and translation.
Its involvement in various cellular processes such as RNA interference and RNA editing makes it a valuable target for research into RNA-based mechanisms of gene regulation and diseases like cancer and viral infections.Understanding the functions and regulatory mechanisms of MOV10 is essential for uncovering its roles in gene expression and RNA processing pathways. By studying MOV10, researchers can gain insights into the molecular mechanisms underlying RNA biology and potentially identify novel therapeutic targets for treating diseases associated with RNA dysregulation.
Product Name:
MOV10 Rabbit Monoclonal Antibody
SKU:
CAB7227
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human MOV10 (Q9HCE1).
Enables 5'-3' RNA helicase activity and RNA binding activity. Involved in defense response to virus; negative regulation of transposition, RNA-mediated; and posttranscriptional regulation of gene expression. Located in P-body and cytosol. Implicated in hypertension.
Purification Method:
Affinity purification
Gene ID:
4343
Clone Number:
ARC1817
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MOV10 Rabbit mAb (CAB7227) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
