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Anti-Mouse Vγ2 TCR In Vivo Antibody - Ultra Low Endotoxin

SKU:
IVMB0075
Product Type:
In Vivo Monoclonal Antibody
Clone:
UC3-10A6
Protein:
V-gamma 2 TCR
Isotype:
Armenian Hamster IgG
Reactivity:
Mouse
Synonyms:
V-gamma 2 T cell receptor
T cell receptor gamma 2
Research Area:
Gamma/Delta T Cell Depletion
Endotoxin Level:
Ultra Low Endotoxin
Host Species:
Armenian Hamster
Applications:
Depletion
FC
IP
$322 - $4,704
Frequently bought together:

Description

system_update_altTechnical Datasheet

Anti-Mouse Vγ2 TCR In Vivo Antibody - Ultra Low Endotoxin

Introducing the Anti-Mouse Vβ2 TCR In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications. This antibody targets the Vβ2 T-cell receptor (TCR), crucial in antigen recognition and immune response, making it ideal for research in immunology and related fields.

With enhanced specificity and ultra-low endotoxin levels (<1.0 EU/mg), it ensures high purity, perfect for ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for stability and efficacy. Enhance your research with this reliable and versatile antibody. The Vβ2 TCR is a component of the T-cell receptor complex found on T-cells, playing a significant role in recognizing peptide antigens presented by major histocompatibility complex (MHC) molecules. This interaction is vital for T-cell activation and subsequent immune responses, making the Anti-Mouse Vβ2 TCR antibody a valuable tool for studying T-cell function and dynamics in various experimental contexts.

Product Name:Anti-Mouse Vγ2 TCR In Vivo Antibody - Ultra Low Endotoxin
Product Code:IVMB0075
Size:1mg, 5mg, 25mg, 50mg, 100mg
Clone:UC3-10A6
Protein:V-gamma2 TCR
Product Type:Monoclonal Antibody
Synonyms:V-gamma2 T-cell receptor, T cell receptor gamma 2
Isotype:Armenian Hamster IgG
Reactivity:Mouse
Immunogen:G8 mouse T cells
Applications:Depletion, FC, IP
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Endotoxin Level:<0.5 EU/mg as determined by the LAL method
Purity: ≥98% monomer by analytical SEC
>95% by SDS Page
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:Depletion, FC, IP
Recommended Usage: FC
It is recommended to use the indirect method for signal enhancement when enumerating cells expressing TCR. A suggested method would be to stain cells expressing TCR with Anti-Mouse TCR at ≤1.0 µg per 1.0 X 106 in a 100 µl total staining volume, followed by Goat.
Reactivity:Mouse
Host Species:Armenian Hamster
Specificity: Armenian Hamster Anti-Mouse V-gamma2 TCR recognizes an epitope on Mouse V-gamma2 TCR. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody was also pathogen tested and third-party certified by IDEXX BioReseach to meet the lowest mycoplasma specification and free of any viral pathogens of concern.
Antigen Distribution: V-gamma 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
Immunogen:G8 mouse T cells
Concentration:≥ 5.0 mg/ml
Endotoxin Level:<0.5 EU/mg as determined by the LAL method
Purity: ≥98% monomer by analytical SEC
>95% by SDS Page
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. Clone UC3-10A6 antibody has been shown to deplete γδ T cells when administered in vivo.

Technical Datasheet:View
Protein:V-gamma2 TCR
Ligand/Receptor:Antigens
Product Thumbnail
Armenian Hamster IgG Isotype Control
Clone PIP
Isotype Armenian Hamster IgG1
Endotoxin Level Ultra Low Endotoxin
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