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Anti-Mouse IFNAR-1 In Vivo Antibody - Ultra Low Endotoxin

SKU:
IVMB0004
Product Type:
In Vivo Monoclonal Antibody
Clone:
MAR1-5A3
Protein:
IFNAR1
Isotype:
Mouse IgG1
Reactivity:
Mouse
Synonyms:
CD118
Ifar
Ifnar
Ifrc
INF-a receptor
Interferon-alpha/beta receptor alpha chain
Endotoxin Level:
Ultra Low Endotoxin
Host Species:
Mouse
Applications:
Blocking
ELISA
FC
IP
WB
€268 - €3,920
Frequently bought together:

Description

system_update_altTechnical Datasheet
Product Name:Anti-Mouse IFNAR-1 In Vivo Antibody - Ultra Low Endotoxin
Product Code:IVMB0004
Size:1mg, 5mg, 25mg, 50mg, 100mg
Clone:MAR1-5A3
Protein:IFNAR1
Product Type:Monoclonal Antibody
Synonyms: CD118, Ifar, Ifnar, Ifrc, INF-a receptor, Interferon-α/β receptor α chain
Isotype:Mouse IgG1
Reactivity:Mouse
Immunogen:Plasmid DNA encoding murine IFNAR1 extracellular domain
Applications:B, ELISA, FC, IP, WB
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Endotoxin Level:<0.5 EU/mg as determined by the LAL method
Purity: ≥98% monomer by analytical SEC
>95% by SDS Page
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Product CodeProduct NameEndotoxin Level
IVMB0004Anti-Mouse IFNAR-1 In Vivo Antibody - Ultra Low EndotoxinUltra Low
IVMB0202Anti-Mouse IFNAR-1 In Vivo Antibody - Low EndotoxinLow
Applications:B, ELISA, FC, IP, WB
Recommended Usage: FC
The suggested concentration for clone MAR1-5A3 antibody for staining cells in flow cytometry is ≤ 2.0 µg per 106 in a volume of 100 µl or 100µl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Reactivity:Mouse
Host Species:Mouse
Specificity:Clone MAR1-5A3 recognizes an epitope on mouse IFNAR1.
Antigen Distribution:IFNAR1 and IFNAR2 are coexpressed on nearly all cells.
Immunogen:Plasmid DNA encoding murine IFNAR1 extracellular domain
Concentration:≥ 5.0 mg/ml
Endotoxin Level:<0.5 EU/mg as determined by the LAL method
Purity: ≥98% monomer by analytical SEC
>95% by SDS Page
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β. Binding and activation of the receptor stimulates Janus protein kinases, which leads to the phosphorylation of several other proteins, namely STAT1 and STAT2. IFNAR1 has also been shown to interact with PRMT1 and Tyrosine kinase 2. Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.

Technical Datasheet:View
Protein:IFNAR1
Ligand/Receptor:IFN-α
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Endotoxin Level Ultra Low Endotoxin
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Product Thumbnail
Mouse IgG1 Isotype Control [HKSP]
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Sales Executive

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