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Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin (IVMB0167)

SKU:
IVMB0167
Antibody Type:
Functional-Grade In Vivo Antibody
Applications:
In Vivo
Disease Area:
Cancer
Clone:
BE29G1
Protein:
ICAM-1
Isotype:
Rat IgG2a
Reactivity:
Mouse
Synonyms:
BB2
CD54
P3.58
Research Area:
Adhesion & Migration
Endotoxin Level:
Ultra Low Endotoxin
Host Species:
Rat
Blocking
IP
WB
€359 - €4,859

Description

system_update_altTechnical Datasheet

Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin

Introducing the Anti-Mouse ICAM-1 [BE29G1] In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications. This antibody targets the ICAM-1 (CD54) protein, which plays a critical role in leukocyte endothelial transmigration, making it ideal for research in immunology, inflammatory responses, and related fields. With a rat IgG2a kappa isotype, it ensures high purity and ultra-low endotoxin levels (<0.01 EU/μg), perfect for ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for stability and efficacy.

Enhance your research with this reliable and versatile antibody. ICAM-1 is a transmembrane glycoprotein expressed on endothelial cells and cells of the immune system. It is essential in the immune system’s inflammatory response by facilitating leukocyte adhesion and transmigration across the endothelium. This makes the Anti-Mouse ICAM-1 [BE29G1] In Vivo Antibody a valuable tool for investigating inflammation, immune cell interactions, and disease mechanisms.

Product Name:Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin
Product Code:IVMB0167
Size:1mg, 5mg, 25mg, 50mg, 100mg
Clone:BE29G1
Protein:ICAM-1
Product Type:Monoclonal Antibody
Synonyms:BB2, CD54, P3.58
Isotype:Rat IgG2a
Reactivity:Mouse
Immunogen:Purified Recombinant Mouse ICAM-1 (>98%)
Applications:B, IP, WB
Formulation:This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Endotoxin Level:<0.5 EU/mg as determined by the LAL method
Purity:≥98% monomer by analytical SEC
>95% by SDS Page
Preparation:Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Product CodeProduct NameEndotoxin Level
IVMB0167Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low EndotoxinUltra Low
IVMB0168Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Low EndotoxinLow
Applications:B, IP, WB
Recommended Usage:WB
Reactivity:Mouse
Host Species:Rat
Specificity:Clone BE29G1 recognizes mouse ICAM-1.
Antigen Distribution:CD54 is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes.
Immunogen:Purified Recombinant Mouse ICAM-1 (>98%)
Concentration:≥ 5.0 mg/ml
Endotoxin Level:<0.5 EU/mg as determined by the LAL method
Purity:≥98% monomer by analytical SEC
>95% by SDS Page
Formulation:This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Preparation:Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

ICAM-1 is a 55 kDa glycoprotein that is part of the Ig superfamily. It is heavily glycosylated to form 75 kDa to 115 kDa. ICAM-1 is known to be an adhesion and viral entry molecule, and its long suspected involevement in signal transduction is being elucidated. The signal-transducing functions of ICAM-1 appear to be mainly associated with proinflammatory pathways. Furthermore, ICAM-1 signaling appears to act as a beacon for inflammatory immune cells such as macrophages and granulocytes bringing about inflammation via lymphocyte trafficking. ICAM-1 is essential for the transmigration of leukocytes out of blood vessels and into tissues, and is a marker of endothelial dysfunction leading to damaging vascular disorders in umbilical and placental vascular tissue of gestational pregnancies. ICAM-1 is the receptor for rhinoviruses (the cause of most common colds) and malaria, and plays an inflammatory role in ocular allergies.

Technical Datasheet:View
Protein:ICAM-1
Research Area:Cell Adhesion, Cell Biology, Neuroscience, Neuroscience Cell Markers
Product Thumbnail
Rat IgG2a Isotype Control
Clone 1-1
Isotype Rat IgG2a
Endotoxin Level Ultra Low Endotoxin
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