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Anti-Mouse/Human PD-L2 (CD273) In Vivo Antibody - Low Endotoxin

SKU:
IVMB0116
Product Type:
In Vivo Monoclonal Antibody
Clone:
3.2.B8
Protein:
PD-L2
Isotype:
Mouse IgG1
Reactivity:
Mouse
Human
Synonyms:
B7-DC
CD273
PDL2
B7DC
Clone 3.2
Research Area:
Immune Checkpoint & Cancer Biology
Endotoxin Level:
Low Endotoxin
Host Species:
Mouse
Applications:
Blocking
FC
€125 - €3,220
Frequently bought together:

Description

system_update_altTechnical Datasheet

Anti-Mouse/Human PD-L2 (CD273) In Vivo Antibody - Low Endotoxin

Introducing the Anti-Mouse/Human PD-L2 (CD273) In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody tailored for in vivo applications. This antibody targets the PD-L2 (CD273) protein, which plays a pivotal role in the regulation of immune responses, making it ideal for immunological research and related fields. With a rat IgG2a isotype, it ensures high purity and low endotoxin levels (<0.1 EU/μg), making it perfect for applications such as ELISA, flow cytometry, functional assays, blocking studies, and in vivo depletion. Available in various sizes, it is formulated in sterile phosphate-buffered saline for optimal stability and efficacy.

Elevate your research endeavors with this dependable and versatile antibody. PD-L2 (CD273) is a member of the B7 family and is primarily expressed on dendritic cells and various tumor cells. It interacts with the PD-1 receptor on T-cells, playing a crucial role in the negative regulation of T-cell activation and tolerance. This interaction is essential for maintaining immune homeostasis and can be exploited by tumors to evade immune surveillance. The Anti-Mouse/Human PD-L2 antibody is invaluable for studying immune regulation, cancer immunotherapy, and the mechanisms of immune checkpoint inhibition.