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Anti-Mouse CTLA-4 (CD152) In Vivo Antibody - Ultra Low Endotoxin

SKU:
IVMB0050
Product Type:
In Vivo Monoclonal Antibody
Clone:
UC10-4F10-11
Protein:
CTLA-4
Isotype:
Armenian Hamster IgG1
Reactivity:
Mouse
Synonyms:
CD152
Cytotoxic T Lymphocyte-Associated Antigen-4
Ly-56
Research Area:
Immune Checkpoint & Cancer Biology
Endotoxin Level:
Ultra Low Endotoxin
Host Species:
Armenian Hamster
Applications:
FA
FC
IP
WB
€355 - €3,920
Frequently bought together:

Description

system_update_altTechnical Datasheet

Anti-Mouse CTLA-4 (CD152) In Vivo Antibody - Ultra Low Endotoxin

Introducing the Anti-Mouse CTLA-4 (CD152) In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for rigorous in vivo applications.

This antibody targets the CTLA-4 protein, a crucial negative regulator of immune responses, making it ideal for research in immunology, cancer, and related fields. With a rat IgG2b kappa isotype, it ensures exceptional purity and ultra-low endotoxin levels (<0.1 EU/mg), perfect for ELISA, flow cytometry, immunohistochemistry, and other biological assays. Available in various sizes, it is formulated in phosphate-buffered saline to maintain stability and efficacy. Elevate your research with this dependable and versatile antibody. CTLA-4, also known as CD152, is an immune checkpoint receptor expressed on T cells. It plays a pivotal role in downregulating immune responses by competing with CD28 for binding to B7 molecules (CD80/CD86) on antigen-presenting cells. By transmitting an inhibitory signal to T cells, CTLA-4 is crucial in maintaining immune homeostasis and preventing autoimmunity. This makes it a significant focus of study in therapeutic interventions for autoimmune diseases, cancer immunotherapy, and transplant biology.