Anti-Mouse CD22 In Vivo Antibody - Ultra Low Endotoxin
Introducing the Anti-Mouse CD22 In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody tailored for in vivo applications. This antibody targets the CD22 protein, an essential molecule involved in B-cell regulation, making it an excellent tool for research in immunology and related disciplines. With its mouse IgG1 isotype, this antibody ensures high purity and ultra-low endotoxin levels (<0.1 EU/mg), making it ideal for applications such as ELISA, flow cytometry, and immunohistochemistry. Available in various sizes, it is meticulously formulated in phosphate-buffered saline to guarantee stability and maximize efficacy.
Elevate your research with this dependable and adaptable antibody.
CD22, also known as a sialoglycoprotein, is prominently expressed on the surface of mature B cells. It plays a pivotal role in modulating B-cell receptor (BCR) signaling and maintaining immune homeostasis. By targeting CD22, researchers can delve deeper into the molecular mechanisms of B-cell functions and related immune responses.
Product Name:
Anti-Mouse CD22 In Vivo Antibody - Ultra Low Endotoxin
Product Code:
IVMB0340
Size:
1 mg, 5 mg, 25 mg, 50 mg, 100 mg
Clone:
Cy34.1
Protein:
CD22
Product Type:
Monoclonal Antibody
Synonyms:
Lyb-8.2
Isotype:
IgG1 k
Reactivity:
Mouse
Applications:
Depletion, FC, In Vivo
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Endotoxin Level:
≤ 0.5 EU/mg as determined by the LAL method
Purity:
≥95% by SDS Page â‹… ≥98% monomer by analytical SEC
Product Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Applications:
Depletion, FC, In Vivo
Reactivity:
Mouse
Host Species:
Mouse
Immunogen:
Mouse B10.D2 Spleen Cells
Concentration:
≥ 5.0 mg/ml
Endotoxin Level:
≤ 0.5 EU/mg as determined by the LAL method
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Purity:
≥95% by SDS Page â‹… ≥98% monomer by analytical SEC
Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Protein:
CD22
Ligand/Receptor:
Associates with SHP-1, Syk, Lck, Lyn and others.
Research Area:
Immunology
Pathogen Testing:
To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Assay Genie's Purified Functional Antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.
