The MNX1/HB9/HLXB9 Monoclonal Antibody (CAB20537) is a valuable tool for researchers studying the MNX1/HB9/HLXB9 protein, which plays a crucial role in the development of motor neurons. This antibody, generated in mouse, is highly specific to human samples and has been validated for use in immunohistochemistry and Western blot applications.MNX1/HB9/HLXB9 is a transcription factor essential for the differentiation of motor neurons in the spinal cord, making it a key player in the development of the nervous system. Dysregulation of this protein has been linked to motor neuron diseases such as spinal muscular atrophy and amyotrophic lateral sclerosis, highlighting its importance in neurodegenerative disorders.
By using the MNX1/HB9/HLXB9 Monoclonal Antibody, researchers can study the expression and function of this protein in various cell types and tissues, paving the way for a better understanding of motor neuron development and disease pathology. This antibody is a valuable tool for studies in neuroscience, developmental biology, and neurodegenerative diseases.
Product Name:
MNX1/HB9/HLXB9 Rabbit Polyclonal Antibody
SKU:
CAB20537
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-315 of human MNX1/HB9/HLXB9 (NP_005506.3).
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3110
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MNX1/HB9/HLXB9 antibody (CAB20537) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
