The MNX1 (HB9, HLXB9) Antibody (CAB19690) is a valuable tool for researchers studying MNX1, a homeobox transcription factor essential for pancreas and motor neuron development. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By binding specifically to the MNX1 protein, this antibody enables the detection and analysis of MNX1 expression in different cell types, making it an ideal choice for studies in developmental biology and neurology.
MNX1, also known as HB9 or HLXB9, plays a crucial role in regulating gene expression and cell differentiation during embryonic development. Its function in pancreas and motor neuron development underscores its importance in understanding diseases like diabetes and motor neuron disorders. Research on MNX1 can provide insights into the molecular mechanisms underlying these conditions and potentially lead to the development of novel therapeutic strategies targeting MNX1 activity.
Product Name:
MNX1/HB9/HLXB9 Rabbit Monoclonal Antibody
SKU:
CAB19690
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MNX1/HB9/HLXB9 (P50219).
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3110
Clone Number:
ARC2233
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MNX1/MNX1/HB9/HLXB9 Rabbit mAb (CAB19690) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
