RBBP7 Rabbit Polyclonal Antibody (CAB13456)
- SKU:
- CAB13456
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- IP
- ChIP
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RBBP7 Rabbit Polyclonal Antibody |
SKU: | CAB13456 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RbAp46/RBBP7 (NP_002884.1). |
Sequence: | MASK EMFE DTVE ERVI NEEY KIWK KNTP FLYD LVMT HALQ WPSL TVQW LPEV TKPE GKDY ALHW LVLG THTS DEQN HLVV ARVH IPND DAQF DASH CDSD KGEF GGFG SVTG KIEC EIKI NHEG EVNR ARYM PQNP HIIA TKTP SSDV LVFD YTKH PAKP DPSG ECNP DLRL RGHQ KEGY GLSW NSNL SGHL LSAS DDHT VCLW DINA GPKE GKIV DAKA IFTG HSAV VE |
Tested Applications: | WB IHC-P IF/ICC ChIP ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 ChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | RbAp46; RbAp46/RBBP7 |
Positive Sample: | HepG2,NIH/3T3,Mouse placenta,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5931 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |