METAP2 Rabbit Monoclonal Antibody (CAB3465)
- SKU:
- CAB3465
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MAP2
- MNPEP
- p67eIF2
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | METAP2 Rabbit Monoclonal Antibody |
SKU: | CAB3465 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-478 of human METAP2 (NP_006829.1). |
Sequence: | CSHY MKNF DVGH VPIR LPRT KHLL NVIN ENFG TLAF CRRW LDRL GESK YLMA LKNL CDLG IVDP YPPL CDIK GSYT AQFE HTIL LRPT CKEV VSRG DDY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | MAP2; MNPEP; p67eIF2; METAP2 |
Positive Sample: | Rat testis,DU 145,HT-1080,NIH/3T3,C6,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm |
Calculated MW: | 53kDa |
Observed MW: | 67kDa |
The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10988 |
Clone Number: | ARC2022 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |