Mesothelin Rabbit Monoclonal Antibody (CAB9180)
- SKU:
- CAB9180
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MPF
- SMRP
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Mesothelin Rabbit Monoclonal Antibody |
SKU: | CAB9180 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human Mesothelin (Q13421). |
Sequence: | YFVK IQSF LGGA PTED LKAL SQQN VSMD LATF MKLR TDAV LPLT VAEV QKLL GPHV EGLK AEER HRPV RDWI LRQR QDDL DTLG LGLQ GGIP NGYL VLDL S |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | MPF; SMRP; Mesothelin |
Positive Sample: | HeLa,OVCAR3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell surface, Endoplasmic reticulum lumen, Extracellular region, Extracellular space, Golgi apparatus, Plasma membrane |
Calculated MW: | 69kDa |
Observed MW: | 40-50kDa |
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 10232 |
Clone Number: | ARC1464 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |