The Anti-Menin Antibody (CAB3395) is a high-quality monoclonal antibody designed for research involving Menin, a protein involved in the regulation of gene expression and cell division. This antibody, produced in mice, exhibits strong reactivity towards human samples and has been validated for use in various applications such as immunohistochemistry and immunofluorescence.Menin plays a crucial role in the development and progression of multiple endocrine neoplasia type 1 (MEN1) syndrome, a hereditary cancer syndrome characterized by tumors in multiple endocrine glands.
Research into the function and regulation of Menin is essential for understanding the molecular mechanisms underlying MEN1 syndrome and other related diseases.The Anti-Menin Antibody (CAB3395) enables specific detection and localization of Menin in tissue samples, making it a valuable tool for studying the role of this protein in cancer development and progression. By investigating the interactions and functions of Menin, researchers can gain insights into potential therapeutic targets for cancer treatment and management.
Product Name:
Menin Rabbit Monoclonal Antibody
SKU:
CAB3395
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 516-615 of human Menin (O00255).
This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones.
Purification Method:
Affinity purification
Gene ID:
4221
Clone Number:
ARC1968
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Menin Rabbit mAb (CAB3395) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
