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MEKK2 Rabbit Monoclonal Antibody (CAB19739)

SKU:
CAB19739
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MEKK2
MEKK2B
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MEKK2 Rabbit Monoclonal Antibody
SKU:CAB19739
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEKK2 (Q9Y2U5).
Sequence:MDDQ QALN SIMQ DLAV LHKA SRPA LSLQ ETRK AKSS SPKK QNDV RVKF EHRG EKRI LQFP RPVK LEDL RSKA KIAF GQSM DLHY TNNE LVIP LTTQ DDLD
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:MEKK2; MEKK2B
Positive Sample:MCF7,Jurkat,Mouse lung
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol, nucleoplasm
Calculated MW:70kDa
Observed MW:78kDa

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Purification Method:Affinity purification
Gene ID:10746
Clone Number:ARC2291
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MEKK2 Rabbit mAb (CAB19739) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.

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