The Anti-MEKK2 Antibody (CAB19739) is a polyclonal antibody specifically designed for research related to MEKK2, a key signaling molecule involved in various cellular processes, including immune response and inflammation regulation. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications.MEKK2, also known as mitogen-activated protein kinase kinase kinase 2, is a critical player in the MAPK signaling pathway, which is essential for cellular responses to external stimuli. By targeting MEKK2 with this antibody, researchers can detect and analyze its expression and activity in different cell types, allowing for insights into its role in immune-related processes such as cytokine production and cell proliferation.
With MEKK2's involvement in diverse physiological and pathological conditions, including cancer and inflammatory disorders, studying its function and regulation can provide valuable information for developing targeted therapies or interventions. This antibody serves as a valuable tool for investigations in immunology, cancer biology, and drug development, offering researchers a means to elucidate the complex interplay of signaling pathways driven by MEKK2.
Product Name:
MEKK2 Rabbit Monoclonal Antibody
SKU:
CAB19739
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEKK2 (Q9Y2U5).
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
Purification Method:
Affinity purification
Gene ID:
10746
Clone Number:
ARC2291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using MEKK2 Rabbit mAb (CAB19739) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
