The MED26 Polyclonal Antibody (CAB20500) is a vital tool for researchers studying MED26, a transcriptional regulator involved in various cellular processes such as gene expression and cell growth. This antibody, produced in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot applications. By binding to the MED26 protein, this antibody enables precise detection and analysis of MED26 in different cell types, making it an essential tool for studies in molecular biology and cancer research.
MED26, also known as CRSP1, is a key player in the regulation of gene transcription and is implicated in the development and progression of various diseases, including cancer. Understanding the role of MED26 in gene regulation is crucial for unraveling its potential therapeutic benefits in cancer treatment and other related conditions. The MED26 Polyclonal Antibody allows researchers to investigate the function and expression of MED26, providing valuable insights into its mechanisms of action and potential therapeutic applications.
Product Name:
MED26 Rabbit Polyclonal Antibody
SKU:
CAB20500
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-574 of human MED26 (NP_004822.2).
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Purification Method:
Affinity purification
Gene ID:
9441
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MED26 Rabbit pAb (CAB20500) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
