The MBD6 Polyclonal Antibody (CAB20148) is a valuable tool for researchers studying MBD6, a protein involved in regulating gene expression through DNA methylation. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blotting applications. By binding to the MBD6 protein, this antibody allows for the detection and analysis of MBD6 in various cell types, making it an ideal choice for studies in epigenetics and gene regulation.MBD6, a member of the MBD protein family, plays a crucial role in interpreting DNA methylation patterns and influencing transcriptional activity.
Understanding the function of MBD6 is essential for unraveling the complexities of gene regulation and its implications in various biological processes, including development, differentiation, and disease. Researchers can use this antibody to further investigate the role of MBD6 in cancer, neurodevelopmental disorders, and other conditions linked to aberrant DNA methylation patterns.
Product Name:
MBD6 Rabbit Polyclonal Antibody
SKU:
CAB20148
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 880-980 of human MBD6 (NP_443129.3).
Enables chromatin binding activity. Located in chromocenter; fibrillar center; and nucleoplasm. Implicated in autism spectrum disorder.
Purification Method:
Affinity purification
Gene ID:
114785
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MBD6 Rabbit pAb (CAB20148) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
