The Anti-MATRIN-3 Antibody (CAB1027) is a crucial tool for researchers studying MATRIN-3, a protein involved in RNA processing and nuclear organization. This polyclonal antibody, derived from rabbits, displays high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to MATRIN-3, this antibody allows for the detection and analysis of this protein in various cellular contexts, making it an essential asset for investigations in molecular biology and disease pathology.MATRIN-3 is known for its role in RNA splicing and transport, as well as its involvement in nuclear matrix organization. Dysregulation of MATRIN-3 has been linked to neurological disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
By studying the function and localization of MATRIN-3 using this antibody, researchers can gain valuable insights into the mechanisms underlying these diseases, potentially leading to the development of targeted therapies.Overall, the Anti-MATRIN-3 Antibody (CAB1027) offers researchers a powerful tool for exploring the functions and implications of MATRIN-3 in various cellular processes and disease states. Its specificity and reliability make it an indispensable resource for those seeking to deepen their understanding of RNA biology and neurodegenerative disorders.
Product Name:
Matrin 3 Rabbit Monoclonal Antibody
SKU:
CAB1027
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Matrin 3 (P43243).
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X.
Purification Method:
Affinity purification
Gene ID:
9782
Clone Number:
ARC1854
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Matrin 3 Rabbit mAb (CAB1027) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
