The MAT2A Polyclonal Antibody (CAB19272) is specifically designed for research involving MAT2A, a key enzyme involved in methionine metabolism and protein synthesis. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in various applications including Western blotting.MAT2A is essential for maintaining cellular methylation balance and its dysregulation has been implicated in various diseases including cancer and liver disorders. By binding to the MAT2A protein, this antibody enables accurate detection and analysis in different cell types, making it an invaluable tool for studies in metabolic regulation, cancer biology, and liver disease research.
Understanding the role of MAT2A in methionine metabolism and protein synthesis is crucial for developing targeted therapies for diseases associated with its dysregulation. This antibody provides researchers with a reliable tool to investigate the function and regulation of MAT2A, paving the way for potential advancements in therapeutic interventions.
Product Name:
MAT2A Rabbit Monoclonal Antibody
SKU:
CAB19272
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAT2A (P31153).
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.
Purification Method:
Affinity purification
Gene ID:
4144
Clone Number:
ARC2447
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAT2A Rabbit mAb (CAB19272) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.