The Mark2 Polyclonal Antibody (CAB6512) is a crucial tool for researchers studying Mark2, a protein kinase involved in various cellular processes including cell growth and division. This antibody, derived from rabbit serum, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Mark2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable asset for studies in cell biology and cancer research.Mark2, also known as Par-1c, plays a pivotal role in cell signaling pathways that regulate cell polarity, migration, and cell cycle progression.
Dysregulation of Mark2 has been implicated in cancer progression and metastasis, making it a target of interest for developing targeted therapies. Understanding the function of Mark2 is essential for uncovering its role in diseases and developing potential treatment strategies.In summary, the Mark2 Polyclonal Antibody (CAB6512) is a valuable tool for researchers investigating the function and significance of the Mark2 protein in various cellular processes and diseases, providing critical insights for the development of new therapeutic approaches.
Product Name:
MARK2 Rabbit Monoclonal Antibody
SKU:
CAB6512
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 689-788 of human MARK2 (Q7KZI7).
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2011
Clone Number:
ARC1862
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MARK2 Rabbit mAb (CAB6512) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
