The MAGOH Polyclonal Antibody (CAB3579) is a valuable tool for researchers studying the MAGOH protein, which plays a key role in RNA processing and splicing. This antibody, derived from rabbits, is highly specific to human samples and has been validated for use in Western blot applications.MAGOH is a crucial component of the exon junction complex (EJC), which is involved in post-transcriptional gene regulation. Dysregulation of MAGOH has been linked to various diseases, including cancer and neurodevelopmental disorders.
By targeting the MAGOH protein, researchers can gain insights into its functions and potential therapeutic implications.This antibody enables the detection and analysis of MAGOH in different cell types, making it ideal for studies in molecular biology, genetics, and developmental biology. With its high specificity and sensitivity, the MAGOH Polyclonal Antibody is a valuable tool for advancing our understanding of RNA processing and its role in human health and disease.
Product Name:
MAGOH Rabbit Monoclonal Antibody
SKU:
CAB3579
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 67-146 of human MAGOH (P61326).
Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts.
Purification Method:
Affinity purification
Gene ID:
4116
Clone Number:
ARC2048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAGOH antibody (CAB3579) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
