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MAD3/MXD3 Rabbit Monoclonal Antibody (CAB19807)

SKU:
CAB19807
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
BHLHC13
MAD3
MYX
Research Area:
Epigenetics and Nuclear Signaling
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MAD3/MXD3 Rabbit Monoclonal Antibody
SKU:CAB19807
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-190 of human MAD3/MXD3 (Q9BW11).
Sequence:RRAR MHIQ KLED QEQR ARQL KERL RSKQ QSLQ RQLE QLRG LAGA AERE RLRA DSLD SSGL SSER SDSD QEEL EVDV ESLV FGGE AELL RGF
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:MYX; MAD3; BHLHC13; MAD3/MXD3
Positive Sample:A549,DU 145,Jurkat
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:23kDa
Observed MW:24kDa

This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.

Purification Method:Affinity purification
Gene ID:83463
Clone Number:ARC2333
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using MAD3/MXD3 Rabbit mAb (CAB19807) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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