The MAD3/MXD3 Polyclonal Antibody (CAB19807) is a valuable tool for researchers studying MAD3/MXD3, a protein known for its role in cell cycle regulation and differentiation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MAD3/MXD3 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for research in developmental biology and cancer biology.
MAD3/MXD3 is a crucial regulator of cell growth and differentiation, with implications in various cellular processes such as apoptosis and proliferation. Its involvement in controlling cell cycle progression underscores its importance in understanding diseases like cancer and developmental disorders. Investigating the function of MAD3/MXD3 with this antibody can provide valuable insights into its impact on cellular pathways and potential therapeutic strategies targeting this protein.
Product Name:
MAD3/MXD3 Rabbit Monoclonal Antibody
SKU:
CAB19807
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-190 of human MAD3/MXD3 (Q9BW11).
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
83463
Clone Number:
ARC2333
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAD3/MXD3 Rabbit mAb (CAB19807) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
