MAD2L1 binding protein Rabbit Monoclonal Antibody (CAB19600)
The MAD2L1BP Polyclonal Antibody (CAB19600) is a valuable tool for researchers studying MAD2L1BP, a protein that plays a crucial role in cell division and chromosome segregation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the MAD2L1BP protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component for research in molecular biology and cancer biology.MAD2L1BP, also known as MAD2L1 binding protein, is involved in the regulation of the cell cycle and ensures accurate distribution of chromosomes during cell division.
Understanding the function of MAD2L1BP is key to unraveling the mechanisms underlying diseases such as cancer, where errors in chromosome segregation can lead to genomic instability and tumor progression. By studying MAD2L1BP, researchers can gain valuable insights into the pathways that drive cancer development and potentially identify new targets for therapeutic intervention.
Product Name:
MAD2L1 binding protein Rabbit Monoclonal Antibody
SKU:
CAB19600
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 175-274 of human MAD2L1BP (Q15013).
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
9587
Clone Number:
ARC2187
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAD2L1BP Rabbit mAb (CAB19600) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
