The LYSRS/KARS Polyclonal Antibody (CAB8648) is a valuable tool for researchers studying the LYSRS/KARS protein, which is involved in the synthesis of lysyl-tRNA and in the regulation of immune responses. This antibody, produced in rabbits, has been shown to be highly specific for human samples and is validated for use in Western blot applications. By binding to the LYSRS/KARS protein, this antibody allows for the detection and analysis of this crucial molecule in various cell types, making it an ideal choice for studies in immunology and cancer research.The LYSRS/KARS protein, also known as lysyl-tRNA synthetase, plays a key role in protein synthesis and immune regulation.
As such, it is a promising target for research on diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the function of LYSRS/KARS is essential for developing new therapies that manipulate immune responses in these disease contexts. With its high specificity and reliable performance, the LYSRS/KARS Polyclonal Antibody (CAB8648) is a valuable tool for researchers working in these important areas of study.
Product Name:
LysRS/KARS Rabbit Monoclonal Antibody
SKU:
CAB8648
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-597 of human LysRS/KARS (Q15046).
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3735
Clone Number:
ARC1765
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using LysRS/KARS Rabbit mAb (CAB8648) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
