The anti-LPAR4 Antibody (CAB20157) is a valuable tool for researchers studying LPAR4, a G-protein coupled receptor involved in cell signaling and inflammation regulation. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the LPAR4 protein, this antibody enables the detection and analysis of LPAR4 expression in various cell types, making it well-suited for studies in immunology and inflammatory disorders.LPAR4, also known as lysophosphatidic acid receptor 4, plays a crucial role in mediating cellular responses to lysophosphatidic acid (LPA), a bioactive lipid molecule with diverse physiological functions.
The dysregulation of LPAR4 signaling has been implicated in various diseases, including cancer, fibrosis, and neurological disorders. Therefore, investigating the function of LPAR4 and its downstream pathways using this antibody may provide insights into the pathogenesis of these conditions and aid in the development of targeted therapies.
Product Name:
LPAR4 Rabbit Polyclonal Antibody
SKU:
CAB20157
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 311-370 of human LPAR4 (Q99677).
This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation.
Purification Method:
Affinity purification
Gene ID:
2846
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LPAR4 Rabbit pAb (CAB20157) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
