The LMBRD2 Polyclonal Antibody (CAB20757) is a valuable tool for researchers studying the role of LMBRD2, a protein involved in cobalamin metabolism and cellular transport processes. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it an excellent choice for Western blot experiments. By targeting the LMBRD2 protein, this antibody allows for accurate identification and examination of LMBRD2 expression levels in various cell types, offering insights into its functions in cellular metabolism and potential implications in diseases such as cobalamin deficiency and related disorders.
LMBRD2, also known as Lysosomal Membrane Protein and Cobalamin Transporter, plays a crucial role in the cellular uptake and processing of cobalamin (vitamin B12), essential for various biological processes including DNA synthesis and nervous system function. Dysfunction of LMBRD2 has been linked to cobalamin-related disorders, highlighting its significance in maintaining overall health and well-being. Research into the mechanisms of LMBRD2 function is vital for developing therapeutic strategies targeting cobalamin metabolism and related conditions, providing potential avenues for the treatment of associated diseases.
Product Name:
LMBRD2 Polyclonal Antibody
SKU:
CAB20757
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-390 of human LMBRD2 (NP_001007528.1).
Involved in adrenergic receptor signaling pathway. Located in membrane.
Purification Method:
Affinity purification
Gene ID:
92255
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using LMBRD2 Rabbit pAb (CAB20757) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
