LMAN1 Rabbit Monoclonal Antibody (CAB4941)
- SKU:
- CAB4941
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ERGIC-53
- ERGIC53
- F5F8D
- FMFD1
- MCFD1
- MR60
- gp58
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LMAN1 Rabbit Monoclonal Antibody |
SKU: | CAB4941 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LMAN1 (P49257). |
Sequence: | MAGS RQRG LRAR VRPL FCAL LLSL GRFV RGDG VGGD PAVA LPHR RFEY KYSF KGPH LVQS DGTV PFWA HAGN AIPS SDQI RVAP SLKS QRGS VWTK TKAA |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | MR60; gp58; F5F8D; FMFD1; MCFD1; ERGIC53; ERGIC-53; LMAN1 |
Positive Sample: | HeLa,293T,NCI-H460,Mouse liver,Mouse brain,Mouse heart,Rat lung,Rat liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi apparatus membrane, Single-pass membrane protein, Single-pass type I membrane protein. |
Calculated MW: | 54kDa |
Observed MW: | 58kDa |
The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.
Purification Method: | Affinity purification |
Gene ID: | 3998 |
Clone Number: | ARC1978 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |