null

LIS1 Rabbit Monoclonal Antibody (CAB3696)

SKU:
CAB3696
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
LIS1
LIS2
MDCR
MDS
NudF
PAFAH
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:LIS1 Rabbit Monoclonal Antibody
SKU:CAB3696
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIS1 (P43034).
Sequence:MVLS QRQR DELN RAIA DYLR SNGY EEAY SVFK KEAE LDVN EELD KKYA GLLE KKWT SVIR LQKK VMEL ESKL NEAK EEFT SGGP LGQK RDPK EWIP RPPE
Tested Applications:WB IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells
Synonyms:MDS; LIS1; LIS2; MDCR; NudF; PAFAH
Positive Sample:U-87MG,Mouse testis,Mouse brain
Conjugate:Unconjugated
Cellular Localization:axon cytoplasm, cell cortex, central region of growth cone, centrosome, cytoplasmic microtubule, cytosol, extracellular exosome, glutamatergic synapse, neuron projection, nuclear envelope, perinuclear region of cytoplasm, Schaffer collateral - CA1 synapse
Calculated MW:47kDa
Observed MW:47kDa

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.

Purification Method:Affinity purification
Gene ID:5048
Clone Number:ARC2075
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using LIS1 Rabbit mAb (CAB3696) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.

Related Products