Lipin 1 Rabbit Monoclonal Antibody (CAB3326)
- SKU:
- CAB3326
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PAP1
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Lipin 1 Rabbit Monoclonal Antibody |
SKU: | CAB3326 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 101-200 of human Lipin 1 (Q14693). |
Sequence: | MHLA TSPI LSEG ASRM ECQL KRGS VDRM RGLD PSTP AQVI APSE TPSS SSVV KKRR KRRR KSQL DSLK RDDN MNTS EDED MFPI EMSS DEAM ELLE SSRT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PAP1; Lipin 1 |
Positive Sample: | HeLa,Hep G2,NIH/3T3,RD,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum membrane, Nucleus membrane, Cytosol |
Calculated MW: | 99kDa |
Observed MW: | 130kDa |
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes.
Purification Method: | Affinity purification |
Gene ID: | 23175 |
Clone Number: | ARC1945 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |