Lin28 Rabbit Monoclonal Antibody (CAB9627)
- SKU:
- CAB9627
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CSDD1
- LIN-28
- LIN28
- ZCCHC1
- lin-28A
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Lin28 Rabbit Monoclonal Antibody |
SKU: | CAB9627 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2). |
Sequence: | MGSV SNQQ FAGG CAKA AEEA PEEA PEDA ARAA DEPQ LLHG AGIC KWFN VRMG FGFL SMTA RAGV ALDP PVDV FVHQ SKLH MEGF RSLK EGEA VEFT FKKS |
Tested Applications: | ELISA IF/IC |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A; LIN28A |
Positive Sample: | Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic stress granule, Cytosol, Nucleolus, Nucleus, P-body, rough endoplasmic reticulum |
Calculated MW: | 23kDa |
Observed MW: | 26kDa |
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
Purification Method: | Affinity purification |
Gene ID: | 79727 |
Clone Number: | ARC1668 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |