The Anti-LIN28 Antibody (CAB9627) is a valuable tool for researchers studying LIN28, a highly conserved RNA binding protein involved in regulating gene expression and stem cell maintenance. This polyclonal antibody, generated in rabbits, shows high specificity and sensitivity towards LIN28 in human samples, making it suitable for a variety of research applications including Western blotting and immunohistochemistry.LIN28 is known to play a crucial role in developmental processes, cell proliferation, and metabolism, and has been implicated in various diseases such as cancer and metabolic disorders.
By targeting LIN28 with this antibody, researchers can further explore its functions and mechanisms in different cell types, providing valuable insights into its potential as a therapeutic target.Overall, the Anti-LIN28 Antibody (CAB9627) is a reliable tool for researchers interested in unraveling the functions and implications of LIN28 in health and disease, offering new opportunities for advancements in basic science and drug discovery.
Product Name:
Lin28 Rabbit Monoclonal Antibody
SKU:
CAB9627
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
Purification Method:
Affinity purification
Gene ID:
79727
Clone Number:
ARC1668
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunofluorescence analysis of paraffin-embedded rat testis using LIN28A Rabbit mAb (CAB9627) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
