The Anti-LILRB2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0319) is a cutting-edge tool for researchers studying LILRB2, a cell surface molecule with implications in immune regulation and cancer progression. This monoclonal antibody, developed using advanced technology, exhibits high specificity and sensitivity towards LILRB2 in human samples, making it an ideal choice for Western blot applications.LILRB2, also known as leukocyte immunoglobulin-like receptor B2, is a key player in immune system modulation, influencing immune responses and potentially serving as a therapeutic target in cancer and autoimmune diseases.
By targeting LILRB2 with this innovative antibody, researchers can gain valuable insights into its function and impact on disease processes, paving the way for novel treatment strategies and personalized medicine approaches.In conclusion, the Anti-LILRB2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0319) offers a powerful tool for dissecting the role of LILRB2 in immune regulation and disease pathogenesis, providing a valuable resource for advancing scientific understanding and improving clinical outcomes.
SKU:
HDAB0319
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC496
Synonyms:
LIR-2, ILT-4, MIR-10, CD85d
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
