The Anti-LCAT Antibody (CAB19228) offered by Assay Genie is a polyclonal antibody tailored for research involving LCAT, an enzyme crucial for the metabolism of cholesterol and the maintenance of healthy lipid profiles. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications including Western blot and immunofluorescence.LCAT, or Lecithin-Cholesterol Acyltransferase, plays a vital role in the reverse cholesterol transport pathway by catalyzing the esterification of cholesterol in lipoproteins. Dysregulation of LCAT activity has been linked to dyslipidemia, atherosclerosis, and cardiovascular diseases, making it a promising target for therapeutic interventions.
By using the Anti-LCAT Antibody, researchers can explore the expression and function of LCAT in different biological contexts, advancing our understanding of lipid metabolism and its implications for human health.This antibody provides a valuable tool for studies in lipid biology, cardiovascular research, and metabolic disorders. Its specificity for LCAT enables precise detection and analysis in a range of sample types, facilitating investigations into the molecular mechanisms underlying lipid homeostasis and disease pathology. Unlock the potential of your research with the Anti-LCAT Antibody from Assay Genie.
Product Name:
LCAT Rabbit Monoclonal Antibody
SKU:
CAB19228
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LCAT (P04180).
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.
Purification Method:
Affinity purification
Gene ID:
3931
Clone Number:
ARC2383
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse plasma, using LCAT antibody (CAB19228) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
