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LAGE3 Rabbit Polyclonal Antibody (CAB20546)

SKU:
CAB20546
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CVG5
ESO3
Pcc1
ITBA2
GAMOS2
DXS9879E
DXS9951E
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:LAGE3 Rabbit Polyclonal Antibody
SKU:CAB20546
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human LAGE3 (NP_006005.2).
Sequence:MRDA DADA GGGA DGGD GRGG HSCR GGVD TAAA PAGG APPA HAPG PGRD AASA ARGS RMRP HIFT LSVP FPTP LEAE IAHG SLAP DAEP HQRV VGKD LTVS GRIL VVRW KAED CRLL RISV INFL DQLS LVVR TMQR FGPP VSR
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:CVG5; ESO3; Pcc1; ITBA2; GAMOS2; DXS9879E; DXS9951E; LAGE3
Positive Sample:HepG2,NCI-H460,BxPC-3
Conjugate:Unconjugated
Cellular Localization:cytoplasm, nuclear body, nucleoplasm, nucleus
Calculated MW:15kDa
Observed MW:17kDa

This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9.

Purification Method:Affinity purification
Gene ID:8270
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using LAGE3 Rabbit pAb (CAB20546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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