Plastin L Rabbit Monoclonal Antibody (CAB4664)
- SKU:
- CAB4664
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CP64
- HEL-S-37
- L-PLASTIN
- LC64P
- LPL
- PLS2
- Research Area:
- Cell Biology
Description
Product Name: | Plastin L Rabbit Monoclonal Antibody |
SKU: | CAB4664 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 528-627 of human L-Plastin/LCP1 (P13796). |
Sequence: | TLRE AKKS SSIS SFKD PKIS TSLP VLDL IDAI QPGS INYD LLKT ENLN DDEK LNNA KYAI SMAR KIGA RVYA LPED LVEV NPKM VMTV FACL MGKG MKRV |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN; L-Plastin/LCP1 |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Actin cytoskeleton, Cytoplasm, Cytosol, Extracellular exosome, Extracellular space, Filopodium, Focal adhesion, Glial cell projection, Perinuclear region of cytoplasm, Phagocytic cup, Plasma membrane, podosome, Ruffle membrane |
Calculated MW: | 70kDa |
Observed MW: | 70kDa |
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
Purification Method: | Affinity purification |
Gene ID: | 3936 |
Clone Number: | ARC2689 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |