Kinesin light chain 1 (KLC1) Rabbit Monoclonal Antibody (CAB19249)
- SKU:
- CAB19249
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KLC1
- KLC
- KNS2
- KNS2A
- kinesin light chain 1
- Research Area:
- Immunology
Description
Product Name: | Kinesin light chain 1 (KLC1) Rabbit Monoclonal Antibody |
SKU: | CAB19249 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Kinesin light chain 1 (KLC1) (Q07866). |
Sequence: | GGWY KACK VDSP TVTT TLKN LGAL YRRQ GKFE AAET LEEA AMRS RKQG LDNV HKQR VAEV LNDP ENME KRRS RESL NVDV VKYE SGPD GGEE VSMS VEWN G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | KLC; KNS2; KNS2A; Kinesin light chain 1 (KLC1) |
Positive Sample: | 293T,MCF7,U-87MG,Mouse brain,Rat brain |
Conjugate: | Unmodified |
Cellular Localization: | Cell projection, Cytoplasm, Cytoplasmic vesicle, cytoskeleton, growth cone |
Calculated MW: | 65kDa |
Observed MW: | 65kDa/75kDa |
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.
Purification Method: | Affinity purification |
Gene ID: | 3831 |
Clone Number: | ARC2409 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |