The Anti-KIAA0196 Antibody (CAB20264) is a powerful tool for researchers studying KIAA0196, a protein implicated in cellular processes and signaling pathways. This antibody, developed using advanced techniques and validated for specificity, is highly reactive with human samples and is ideal for use in various experimental applications, including immunofluorescence and immunohistochemistry.KIAA0196, also known as FAM40B, is a protein of interest due to its involvement in cell growth, migration, and intracellular signaling. Its dysregulation has been linked to diseases such as cancer, making it a promising target for therapeutic interventions.
The Anti-KIAA0196 Antibody enables precise detection and analysis of KIAA0196 protein levels in different cell types, providing valuable insights into its function and potential implications in disease development.Researchers studying cellular biology, signal transduction, and cancer biology will benefit from using the Anti-KIAA0196 Antibody in their experiments. By understanding the role of KIAA0196 in cellular processes, researchers can uncover new therapeutic approaches and potential targets for drug development.
Product Name:
KIAA0196 Rabbit Polyclonal Antibody
SKU:
CAB20264
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 380-530 of human KIAA0196 (NP_055661.3).
cytosol, early endosome, endoplasmic reticulum, endosome, nucleoplasm, WASH complex
Calculated MW:
134kDa
Observed MW:
134kDa
This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases.
Purification Method:
Affinity purification
Gene ID:
9897
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse thymus, using KIAA0196 Rabbit pAb (CAB20264) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 300s.
