The Anti-KDM1/LSD1 Polyclonal Antibody (CAB8711) is a valuable tool for researchers studying lysine-specific demethylase 1 (LSD1), a key epigenetic regulator involved in gene expression and cell differentiation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blot applications.LSD1 is known to play crucial roles in diverse biological processes, such as embryonic development, differentiation, and oncogenesis. By targeting LSD1, researchers can gain insight into its function and potential therapeutic implications in cancer and other diseases.
The Anti-KDM1/LSD1 Antibody enables the detection and analysis of LSD1 protein levels in various cell types, facilitating a deeper understanding of its role in epigenetic regulation.With its ability to specifically recognize LSD1, this antibody is a valuable tool for scientists studying epigenetics, cancer biology, and drug development. By targeting LSD1, researchers can elucidate the complex mechanisms by which epigenetic modifications influence gene expression and cellular function, paving the way for the development of novel treatments targeting LSD1 in various disease contexts.
Product Name:
KDM1/LSD1 Rabbit Monoclonal Antibody
SKU:
CAB8711
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-811 of human KDM1 / LSD1 (NP_055828.2).
This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23028
Clone Number:
ARC1160
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using KDM1 / LSD1 Rabbit mAb (CAB8711) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
