The Anti-KAT13A (SRC1) Antibody (CAB9058) is a valuable tool for researchers studying KAT13A, a member of the histone acetyltransferase family that plays a key role in gene regulation. This polyclonal antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By binding to the KAT13A protein, this antibody enables the detection and analysis of KAT13A expression in various cell types, making it an essential tool for studies in epigenetics and cancer research.
KAT13A, also known as SRC1, is involved in the acetylation of histone proteins, which is a crucial mechanism for regulating gene expression. Dysregulation of KAT13A has been implicated in various diseases, including cancer and metabolic disorders, making it an attractive target for therapeutic intervention. Research into KAT13A activity is essential for uncovering its role in disease pathogenesis and developing novel treatment strategies targeting this histone modifier.
Product Name:
KAT13A/SRC1 Rabbit Monoclonal Antibody
SKU:
CAB9058
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human KAT13A / SRC1 (Q15788).
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
8648
Clone Number:
ARC1395
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using KAT13A / SRC1 Rabbit mAb (CAB9058) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
