The Jund Polyclonal Antibody (CAB5496) is a vital tool for researchers studying the Jund protein, a transcription factor involved in various cellular processes, including inflammation and cell growth. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Jund protein, this antibody enables precise detection and analysis in a variety of cell types, making it essential for investigations in immunology, oncology, and cell signaling pathways.
Jund is known to play a crucial role in regulating gene expression in response to various stimuli, such as stress and growth factors. Its involvement in cell proliferation, differentiation, and apoptosis makes it a key target for research into diseases like cancer, cardiovascular disorders, and neurodegenerative diseases. Understanding the function of Jund is essential for identifying potential therapeutic targets and developing new treatments in these disease contexts.
Product Name:
JunD Rabbit Monoclonal Antibody
SKU:
CAB5496
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-141 of human JunD (P17535).
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
AP-1; JunD
Positive Sample:
HeLa,HT-1080
Conjugate:
Unconjugated
Cellular Localization:
Nucleoplasm, Nucleus
Calculated MW:
35kDa
Observed MW:
38kDa/42kDa
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216).
Purification Method:
Affinity purification
Gene ID:
3727
Clone Number:
ARC1409
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using JunD Rabbit mAb (CAB5496) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
