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JMJD1C Rabbit Polyclonal Antibody (CAB20153)

SKU:
CAB20153
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
KDM3C
TRIP8
TRIP-8
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:JMJD1C Rabbit Polyclonal Antibody
SKU:CAB20153
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 354-448 of human JMJD1C (NP_116165.1).
Sequence:KPEE DEKK LNMK RLRT DNVS DFSE SSDS ENSN KRII DNSS EQKP ENEL KNKN TSKI NGEE GKPH NNEK AGEE TLKN SQPP WDQI QEDK KHEE AEK
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:KDM3C; TRIP8; TRIP-8; JMJD1C
Positive Sample:HeLa,HepG2,Jurkat,Mouse testis
Conjugate:Unconjugated
Cellular Localization:histone deacetylase complex, nucleoplasm
Calculated MW:285kDa
Observed MW:285kDa

The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:221037
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using JMJD1C Rabbit pAb (CAB20153) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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