The JAG2 Polyclonal Antibody (CAB19267) is a valuable tool for researchers studying JAG2, a key protein involved in cellular signaling pathways and development processes. This antibody, generated in rabbits, is highly specific for detecting JAG2 in human samples and is validated for use in various applications, including Western blotting.JAG2, a member of the Notch signaling pathway, plays a critical role in regulating cell differentiation, proliferation, and survival. Dysregulation of JAG2 has been implicated in various diseases, including cancer and developmental disorders.
By targeting JAG2, researchers can gain insights into how this protein influences cellular processes and potentially identify new therapeutic targets for disease intervention.This antibody enables researchers to detect and analyze JAG2 expression in different cell types, making it suitable for studies in developmental biology, oncology, and regenerative medicine. By understanding the function of JAG2, researchers can uncover new avenues for treatment and further elucidate the role of this protein in normal and disease states.
Product Name:
JAG2 Rabbit Monoclonal Antibody
SKU:
CAB19267
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human JAG2 (Q9Y219).
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3714
Clone Number:
ARC2438
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using JAG2 Rabbit mAb (CAB19267) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
