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IRF6 Rabbit Monoclonal Antibody (CAB3209)

SKU:
CAB3209
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
LPS
OFC6
PIT
PPS
PPS1
VWS
VWS1
Research Area:
Developmental Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:IRF6 Rabbit Monoclonal Antibody
SKU:CAB3209
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 368-467 of human IRF6 (O14896).
Sequence:PFEI YLCF GEEW PDGK PLER KLIL VQVI PVVA RMIY EMFS GDFT RSFD SGSV RLQI STPD IKDN IVAQ LKQL YRIL QTQE SWQP MQPT PSMQ LPPA LPPQ
Tested Applications:WB IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1; IRF6
Positive Sample:293T,HepG2,A-549,Mouse lung,Mouse kidney,Rat lung,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:53kDa
Observed MW:68kDa

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:3664
Clone Number:ARC1928
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using IRF6 Rabbit mAb (CAB3209) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.

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