The IQGAP1 Polyclonal Antibody (CAB9765) is a high-quality research tool designed for studies involving IQGAP1, a key regulator of cell signaling and cytoskeletal dynamics. This antibody, derived from rabbits, has been extensively validated for use in Western blot applications and shows strong reactivity with human samples.IQGAP1 is a scaffolding protein that plays a vital role in diverse cellular processes, including cell adhesion, migration, and proliferation. Its overexpression has been linked to various diseases, such as cancer and neurological disorders, making it an attractive target for therapeutic interventions.
By targeting IQGAP1 with this specific antibody, researchers can gain valuable insights into its functions and interactions within cellular pathways. This antibody is an essential tool for advancing research in cancer biology, neuroscience, and cell biology, providing a deeper understanding of the role of IQGAP1 in health and disease.
Product Name:
IQGAP1 Rabbit Monoclonal Antibody
SKU:
CAB9765
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IQGAP1 (NP_003861.1).
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
Purification Method:
Affinity purification
Gene ID:
8826
Clone Number:
ARC1739
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using IQGAP1 Rabbit mAb (CAB9765) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
