The Anti-Interferon Alpha 1 (IFN-alpha1) Antibody (CAB21081) is a valuable tool for researchers studying the immune system. Interferon alpha 1 is a key cytokine involved in antiviral responses and immune regulation. This polyclonal antibody, produced in rabbits, is highly specific and reactive with human samples. It has been validated for use in Western blot applications, allowing for the detection and analysis of IFN-alpha1 protein levels in various cell types.IFN-alpha1 plays a crucial role in modulating immune responses and has been implicated in various disease states, including viral infections and autoimmune disorders.
By utilizing this antibody, researchers can better understand the role of IFN-alpha1 in immune function and its potential therapeutic implications. This antibody is an essential tool for studies in immunology, virology, and autoimmune research, providing valuable insights into the complex interplay of the immune system.
Product Name:
Interferon alpha 1 (IFN-α1) Monoclonal Antibody
SKU:
CAB21081
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-189 of human Interferon alpha 1 (IFN-α1) (NP_076918.1).
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
Purification Method:
Affinity purification
Gene ID:
3439
Clone Number:
ARC52133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of recombinant Human IFNA1 Protein, using Interferon alpha 1 (IFN-α1) Rabbit mAb (CAB21081) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at1:10000 dilution.Lysates/proteins: 10ng/5ng per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
