The Anti-ILF2 Antibody (CAB9530) is a high-quality polyclonal antibody designed for research involving ILF2, a protein known to play a role in gene regulation and RNA processing. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in various applications such as Western blotting.ILF2, also known as interleukin enhancer-binding factor 2, is involved in various cellular processes, including transcriptional regulation and mRNA stability. It is linked to diseases like cancer and autoimmune disorders, making it a valuable target for investigations in molecular biology and immunology.
By targeting ILF2, researchers can gain insights into its functions and potential therapeutic applications in disease management.Overall, the Anti-ILF2 Antibody (CAB9530) is a valuable tool for researchers looking to study ILF2 and its roles in gene expression and disease pathways. Its specificity and reliability make it suitable for a wide range of research applications, contributing to advancements in understanding ILF2 biology and its implications in human health.
Product Name:
ILF2 Rabbit Monoclonal Antibody
SKU:
CAB9530
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ILF2 (Q12905).
The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.
Purification Method:
Affinity purification
Gene ID:
3608
Clone Number:
ARC1621
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ILF2 Rabbit mAb (CAB9530) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
