ILF2 Rabbit Monoclonal Antibody (CAB9530)
- SKU:
- CAB9530
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NF45
- PRO3063
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | ILF2 Rabbit Monoclonal Antibody |
SKU: | CAB9530 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ILF2 (Q12905). |
Sequence: | SALA AIRH ARWF EENA SQST VKVL IRLL KDLR IRFP GFEP LTPW ILDL LGHY AVMN NPTR QPLA LNVA YRRC LQIL AAGL FLPG SVGI TDPC ESGN FRVH T |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | NF45; PRO3063; ILF2 |
Positive Sample: | HeLa,HepG2,Raji,Mouse thymus,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | extracellular region, nucleolus, nucleoplasm, nucleus |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.
Purification Method: | Affinity purification |
Gene ID: | 3608 |
Clone Number: | ARC1621 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |