The Anti-IL7RA Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0230) is a cutting-edge tool for researchers studying IL7RA, an important cell surface receptor involved in immune cell development and function. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for human IL7RA samples, making it an ideal choice for various experimental applications such as immunohistochemistry and flow cytometry.IL7RA, also known as CD127, plays a crucial role in the development and survival of T cells, making it a key target for research in immunology, cancer, and autoimmune diseases.
By targeting this receptor, researchers can gain valuable insights into the mechanisms underlying immune dysfunction and potential therapeutic interventions.The Anti-IL7RA Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0230) offers a reliable tool for researchers looking to investigate the role of IL7RA in immune function and disease pathogenesis. With its high specificity and versatility, this antibody is a valuable asset for advancing our understanding of immune regulation and developing novel treatment strategies.
SKU:
HDAB0230
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC272
Synonyms:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
