The Anti-IL5 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0232) is a powerful tool for researchers studying IL5, a cytokine involved in allergic and inflammatory responses. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting IL5 in human samples, making it ideal for use in various immunoassays and immunohistochemistry techniques. By targeting the IL5 protein, researchers can gain valuable insights into the role of IL5 in diseases such as asthma, allergic rhinitis, and eosinophilic disorders.
IL5, a key player in the regulation of eosinophil development and activation, is a promising target for the development of therapies for allergic and inflammatory diseases. The Anti-IL5 Chimeric Recombinant Rabbit Monoclonal Antibody provides researchers with a valuable tool to investigate the functions of IL5 in these contexts, paving the way for the development of novel therapeutic strategies targeting IL5-mediated immune responses.
SKU:
HDAB0232
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC274
Synonyms:
IL-5,TRF,Interleukin-5,EDF
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
