IL12A Rabbit Polyclonal Antibody (CAB20383)
- SKU:
- CAB20383
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- P35
- CLMF
- NFSK
- NKSF1
- IL-12A
Frequently bought together:
Description
Product Name: | IL12A Rabbit Polyclonal Antibody |
SKU: | CAB20383 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IL12A (NP_000873.2). |
Sequence: | LDHL SLAR NLPV ATPD PGMF PCLH HSQN LLRA VSNM LQKA RQTL EFYP CTSE EIDH EDIT KDKT STVE ACLP LELT KNES CLNS RETS FITN GSCL ASRK T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | P35; CLMF; NFSK; NKSF1; IL-12A; IL12A |
Positive Sample: | RAW264.7,Recombinant Human IL12A/NKSF1 Protein |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum lumen, extracellular region, extracellular space, interleukin-12 complex, late endosome lumen |
Calculated MW: | 25kDa |
Observed MW: | 35kDa/75kDa |
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Purification Method: | Affinity purification |
Gene ID: | 3592 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |